|
|
pyruvate + (S)-methylmalonyl-CoA <=> oxaloacetate + propionyl-CoA
|
2.1.3.1
methylmalonyl-CoA carboxytransferase
|
–
|
| |
BRENDA:
BR43948
KEGG:
R00930
MetaCyc:
2.1.3.1-RXN
|
|
|
|
(S)-methylmalonyl-CoA + H+ <=> CO2 + propionyl-CoA
|
2.3.1.226
carboxymethylproline synthase
4.1.1
4.1.1.9
malonyl-CoA decarboxylase
4.1.1.94
ethylmalonyl-CoA decarboxylase
4.1.1.M5
6.4.1.3
propionyl-CoA carboxylase
|
–
–
–
–
–
–
|
| |
BRENDA:
BS1620;
BS410118
KEGG:
R00923;
R05373
MetaCyc:
METHYLMALONYL-COA-DECARBOXYLASE-RXN;
RXN0-310
SABIO-RK:
4979
|
|
|
|
(R)-2-methylmalonyl-CoA <=> (S)-methylmalonyl-CoA
|
5.1.99.1
methylmalonyl-CoA epimerase
|
–
|
| |
BRENDA:
BR204;
BS970
KEGG:
R02765
MetaCyc:
METHYLMALONYL-COA-EPIM-RXN
SABIO-RK:
2642
|
|
|
|
(S)-methylmalonyl-CoA + H+ <=> CO2 + propionyl-CoA
|
2.3.1.226
carboxymethylproline synthase
4.1.1
4.1.1.9
malonyl-CoA decarboxylase
4.1.1.94
ethylmalonyl-CoA decarboxylase
4.1.1.M5
6.4.1.3
propionyl-CoA carboxylase
|
–
–
–
–
–
–
|
| |
BRENDA:
BS1620;
BS410118
KEGG:
R00923;
R05373
MetaCyc:
METHYLMALONYL-COA-DECARBOXYLASE-RXN;
RXN0-310
SABIO-RK:
4979
|
|
|
|
propionyl-CoA + H2O + oxaloacetate <=> (2S,3S)-methylcitrate + CoA + H+
|
2.3.3.16
citrate synthase (unknown stereospecificity)
2.3.3.5
2-methylcitrate synthase
|
–
–
|
| |
BRENDA:
BR44127;
BS321797;
BS407305
KEGG:
R00931
MetaCyc:
2-METHYLCITRATE-SYNTHASE-RXN
SABIO-RK:
1249
|
|
|
|
(R)-2-methylmalonyl-CoA <=> succinyl-CoA
|
5.4.99.2
methylmalonyl-CoA mutase
5.4.99.63
ethylmalonyl-CoA mutase
5.4.99.64
2-hydroxyisobutanoyl-CoA mutase
|
–
–
–
|
| |
BRENDA:
BR249;
BS380077;
BS390473
KEGG:
R00833
MetaCyc:
METHYLMALONYL-COA-MUT-RXN
SABIO-RK:
10453;
1174
|
|
|
|
(2S,3S)-methylcitrate <=> (Z)-2-methylaconitate + H2O
|
4.2.1.117
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.79
2-methylcitrate dehydratase
|
–
–
|
| |
BRENDA:
BR456;
BS2113;
BS444085
KEGG:
R04424
MetaCyc:
2-METHYLCITRATE-DEHYDRATASE-RXN
SABIO-RK:
4111
|
|
|
|
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> (Z)-2-methylaconitate + H2O
|
4.2.1.3
aconitate hydratase
4.2.1.99
2-methylisocitrate dehydratase
|
–
–
|
| |
BRENDA:
BR471;
BS18710;
BS368299
KEGG:
R04425
MetaCyc:
4.2.1.99-RXN
SABIO-RK:
4112
|
|
|
|
propionyl-CoA + succinate <=> propionate + succinyl-CoA
|
2.8.3
2.8.3.1
propionate CoA-transferase
2.8.3.18
succinyl-CoA:acetate CoA-transferase
2.8.3.M4
|
–
–
–
–
|
| |
BRENDA:
BS428954
KEGG:
R11773
MetaCyc:
RXN0-268
SABIO-RK:
14385
|
|
|
|
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> succinate + pyruvate
|
4.1.3.1
isocitrate lyase
4.1.3.30
methylisocitrate lyase
|
–
–
|
| |
BRENDA:
BR390;
BS417300
KEGG:
R00409
MetaCyc:
METHYLISOCITRATE-LYASE-RXN
SABIO-RK:
866
|
|
